Comparison of psychotropic drug preferences and side effects in old and young patients with schizophrenia and schizoaffective disorder

نویسندگان

چکیده

Purpose: The current study investigates the preferred psychotropic drug treatments and their tolerability in elderly patients (EP) with a diagnosis of schizophrenia or schizoaffective disorder compared to younger (YP).
 Materials Methods: included 154 EP 195 YP schizophrenia/schizoaffective admitted outpatient unit at university hospital last decade. medical records were reviewed. types doses antipsychotic drugs used by each patient, use other drugs, ongoing complaints, drug-related side effects compliance treatment also examined.
 Results: Second generation was higher (88% YP, 80% EP). Antipsychotic equivalent found 266.63 mg EP, 522.21 that group. clozapine (7% 37% YP) mood stabilizers (4.5% 18% YP. There rate dose reduction (21.5% 52% When groups terms reasons reduction, it more frequent due (21.4% 40% EP), while remission common (78.6% 60% EP) .
 Conclusion: Lower antipsychotics suggests milder symptoms lower tolerability. stabilizer can be explained avoiding like extrapyramidal, cardiovascular metabolic are EP.

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ژورنال

عنوان ژورنال: Cukurova Medical Journal

سال: 2022

ISSN: ['2602-3040', '2602-3032']

DOI: https://doi.org/10.17826/cumj.1139145